System and method for synthesis of DNA particles and use thereof

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Keyword

System and method for synthesis of DNA particles and use thereof

Sukurta: 03 July 2023
Kryptis: Biotechnologijos

The present invention relates to system and method for production of DNA particles and use thereof. The DNA particles can be produced by amplification of nucleic acid molecule(s). Alternatively, DNA particles can be prepared by condensing multiple DNA molecules. The DNA condensation into a particle is mainly triggered by pyrophosphate and positively charged cations (e.g. magnesium). DNA particles can be applied for numerous biological applications but not limited to directed evolution, proteomics, drug delivery and imaging. DNA particles can be used to synthesize proteins using in vitro. transcription/translation reaction.

Inventors: Linas Mažutis; Greta Stonytė; Vaidotas Kiseliovas; Rapolas Žilionis; Arvydas Janulaitis; Robertas Galinis; Sabine Studer; Donald Hilvert. 

Jurisdiction: EP, US

Link to espacenet.